# NCA Calculation and Population PK Model Diagnosis

## Documentation for package ‘ncappc’ version 0.2.1.1

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

calc.stat | Calculates a set of statistics for a given array of numbers.
dv.plot | Plots drug plasma concentration vs time data
est.nca | Estimates individual NCA metrics from concentration vs time data. data.
histobs.plot | Plots histogram of selected set of NCA metrics.
histpop.plot | Plots population histogram of the NCA metrics selected for model diagnosis.
nca.deviation.plot | Plot individual deviation of NCA metrics estimated from observed and simulated data
nca.npde | Calculates individual normalized prediction distribution errors (NPDE) from PDE data.
nca.npde.plot | Plots population histogram of the NCA metrics selected for model diagnosis.
nca.pde.deviation.outlier | Calculates individual prediction distribution errors (PDE) and scaled deviation of NCA metrics estimated from observed and simulated data. Identifies outlier to population PK model.
ncappc | Performs NCA calculations and population PK model diagnosis.
read_nm_table | Read nonmem table files produced.